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Combined with the sleep disruptions and energy fluctuations of perimenopause, some women feel significantly more tired during the initial adjustment period
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Gastrointestinal symptoms that some patients experience while on GLP-1 therapy—such as nausea, reduced appetite, or altered bowel habits—generally resolve as the medication clears from the system, typically within 1-2 weeks for short-acting formulations and within 4-8 weeks for long-acting preparations, corresponding to their elimination timelines
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